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dna origami nanostructures  (Thermo Fisher)


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    Thermo Fisher dna origami nanostructures
    Starting, from left to right, the assembly of <t>DNA</t> origami <t>nanostructures,</t> in three different shapes (rods, icosahedrons and rectangles); their exposure to temperature, pH, MgCl 2 concentration, incubation time and DNase I concentration values; analysis of their stability by dynamic light scattering and generation of the ML model.
    Dna Origami Nanostructures, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dna+origami+nanostructures/bio_rxiv__2025__07__18__665506-120-5-12?v=Thermo+Fisher
    Average 99 stars, based on 1 article reviews
    dna origami nanostructures - by Bioz Stars, 2026-07
    99/100 stars

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    1) Product Images from "Predicting DNA origami stability in physiological media by machine learning"

    Article Title: Predicting DNA origami stability in physiological media by machine learning

    Journal: bioRxiv

    doi: 10.1101/2025.07.18.665506

    Starting, from left to right, the assembly of DNA origami nanostructures, in three different shapes (rods, icosahedrons and rectangles); their exposure to temperature, pH, MgCl 2 concentration, incubation time and DNase I concentration values; analysis of their stability by dynamic light scattering and generation of the ML model.
    Figure Legend Snippet: Starting, from left to right, the assembly of DNA origami nanostructures, in three different shapes (rods, icosahedrons and rectangles); their exposure to temperature, pH, MgCl 2 concentration, incubation time and DNase I concentration values; analysis of their stability by dynamic light scattering and generation of the ML model.

    Techniques Used: Concentration Assay, Incubation

    ( A ) Schematic representation of the components and formation of DNA origami nanostructures. ( B ) 3D rendered representation of the icosahedrons, rectangles and rods, and their corresponding AFM images (scale bar = 200 nm; heigh values in nm). ( C ) DLS characterization of the three origami shapes. D) GE of purified and unpurified origami shapes, where 1 is M13 scaffold, 2 unpurified icosahedrons, 3 purified icosahedrons, 4 unpurified rectangles, 5 purified rectangles, 6 p7560 scaffold, 7 unpurified rods and 8 purified rods. Sc refers to the scaffold, St to staples and DO to DNA origami.
    Figure Legend Snippet: ( A ) Schematic representation of the components and formation of DNA origami nanostructures. ( B ) 3D rendered representation of the icosahedrons, rectangles and rods, and their corresponding AFM images (scale bar = 200 nm; heigh values in nm). ( C ) DLS characterization of the three origami shapes. D) GE of purified and unpurified origami shapes, where 1 is M13 scaffold, 2 unpurified icosahedrons, 3 purified icosahedrons, 4 unpurified rectangles, 5 purified rectangles, 6 p7560 scaffold, 7 unpurified rods and 8 purified rods. Sc refers to the scaffold, St to staples and DO to DNA origami.

    Techniques Used: Purification

    ( A ) Schematic representation of the change of diffusion coefficient, as measured by DLS, upon destabilization of the DNA nanostructure. The relationship between the radius and diffusion coefficient is provided to aid understanding. D is diffusion coefficient, k B Boltzmann’s constant, T temperature and μ solvent viscosity. ( B ) Diffusion coefficient values measured via DLS for each shape at different experimental conditions (temperature, MgCl 2 concentration, incubation time, pH and DNase I concentration). Error bars represent the standard error of the mean. All p-values were computed from the unpaired t-test with unequal variance with respect to the diffusion coefficient at 4°C; *p-value ≤ 0.05; **p-value ≤ 0.01, ***p-value ≤ 0.001, ****p-value ≤ 0.0001. ( C ) Representative AFM height images corresponding to the control (4°C) and two unstable conditions (60°C and 0.2 U/mL of DNase I) depict the different ways in which loss of structural stability occurs, leading to different diffusion coefficient values (scale bar = 100 nm).
    Figure Legend Snippet: ( A ) Schematic representation of the change of diffusion coefficient, as measured by DLS, upon destabilization of the DNA nanostructure. The relationship between the radius and diffusion coefficient is provided to aid understanding. D is diffusion coefficient, k B Boltzmann’s constant, T temperature and μ solvent viscosity. ( B ) Diffusion coefficient values measured via DLS for each shape at different experimental conditions (temperature, MgCl 2 concentration, incubation time, pH and DNase I concentration). Error bars represent the standard error of the mean. All p-values were computed from the unpaired t-test with unequal variance with respect to the diffusion coefficient at 4°C; *p-value ≤ 0.05; **p-value ≤ 0.01, ***p-value ≤ 0.001, ****p-value ≤ 0.0001. ( C ) Representative AFM height images corresponding to the control (4°C) and two unstable conditions (60°C and 0.2 U/mL of DNase I) depict the different ways in which loss of structural stability occurs, leading to different diffusion coefficient values (scale bar = 100 nm).

    Techniques Used: Diffusion-based Assay, Solvent, Viscosity, Concentration Assay, Incubation, Control



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    Image Search Results


    Starting, from left to right, the assembly of DNA origami nanostructures, in three different shapes (rods, icosahedrons and rectangles); their exposure to temperature, pH, MgCl 2 concentration, incubation time and DNase I concentration values; analysis of their stability by dynamic light scattering and generation of the ML model.

    Journal: bioRxiv

    Article Title: Predicting DNA origami stability in physiological media by machine learning

    doi: 10.1101/2025.07.18.665506

    Figure Lengend Snippet: Starting, from left to right, the assembly of DNA origami nanostructures, in three different shapes (rods, icosahedrons and rectangles); their exposure to temperature, pH, MgCl 2 concentration, incubation time and DNase I concentration values; analysis of their stability by dynamic light scattering and generation of the ML model.

    Article Snippet: The final concentration of the DNA origami nanostructures was determined via the NanoDrop UV-Vis spectrophotometer (Thermo Fisher Scientific) by measuring the absorption at a wavelength of 260 nm.

    Techniques: Concentration Assay, Incubation

    ( A ) Schematic representation of the components and formation of DNA origami nanostructures. ( B ) 3D rendered representation of the icosahedrons, rectangles and rods, and their corresponding AFM images (scale bar = 200 nm; heigh values in nm). ( C ) DLS characterization of the three origami shapes. D) GE of purified and unpurified origami shapes, where 1 is M13 scaffold, 2 unpurified icosahedrons, 3 purified icosahedrons, 4 unpurified rectangles, 5 purified rectangles, 6 p7560 scaffold, 7 unpurified rods and 8 purified rods. Sc refers to the scaffold, St to staples and DO to DNA origami.

    Journal: bioRxiv

    Article Title: Predicting DNA origami stability in physiological media by machine learning

    doi: 10.1101/2025.07.18.665506

    Figure Lengend Snippet: ( A ) Schematic representation of the components and formation of DNA origami nanostructures. ( B ) 3D rendered representation of the icosahedrons, rectangles and rods, and their corresponding AFM images (scale bar = 200 nm; heigh values in nm). ( C ) DLS characterization of the three origami shapes. D) GE of purified and unpurified origami shapes, where 1 is M13 scaffold, 2 unpurified icosahedrons, 3 purified icosahedrons, 4 unpurified rectangles, 5 purified rectangles, 6 p7560 scaffold, 7 unpurified rods and 8 purified rods. Sc refers to the scaffold, St to staples and DO to DNA origami.

    Article Snippet: The final concentration of the DNA origami nanostructures was determined via the NanoDrop UV-Vis spectrophotometer (Thermo Fisher Scientific) by measuring the absorption at a wavelength of 260 nm.

    Techniques: Purification

    ( A ) Schematic representation of the change of diffusion coefficient, as measured by DLS, upon destabilization of the DNA nanostructure. The relationship between the radius and diffusion coefficient is provided to aid understanding. D is diffusion coefficient, k B Boltzmann’s constant, T temperature and μ solvent viscosity. ( B ) Diffusion coefficient values measured via DLS for each shape at different experimental conditions (temperature, MgCl 2 concentration, incubation time, pH and DNase I concentration). Error bars represent the standard error of the mean. All p-values were computed from the unpaired t-test with unequal variance with respect to the diffusion coefficient at 4°C; *p-value ≤ 0.05; **p-value ≤ 0.01, ***p-value ≤ 0.001, ****p-value ≤ 0.0001. ( C ) Representative AFM height images corresponding to the control (4°C) and two unstable conditions (60°C and 0.2 U/mL of DNase I) depict the different ways in which loss of structural stability occurs, leading to different diffusion coefficient values (scale bar = 100 nm).

    Journal: bioRxiv

    Article Title: Predicting DNA origami stability in physiological media by machine learning

    doi: 10.1101/2025.07.18.665506

    Figure Lengend Snippet: ( A ) Schematic representation of the change of diffusion coefficient, as measured by DLS, upon destabilization of the DNA nanostructure. The relationship between the radius and diffusion coefficient is provided to aid understanding. D is diffusion coefficient, k B Boltzmann’s constant, T temperature and μ solvent viscosity. ( B ) Diffusion coefficient values measured via DLS for each shape at different experimental conditions (temperature, MgCl 2 concentration, incubation time, pH and DNase I concentration). Error bars represent the standard error of the mean. All p-values were computed from the unpaired t-test with unequal variance with respect to the diffusion coefficient at 4°C; *p-value ≤ 0.05; **p-value ≤ 0.01, ***p-value ≤ 0.001, ****p-value ≤ 0.0001. ( C ) Representative AFM height images corresponding to the control (4°C) and two unstable conditions (60°C and 0.2 U/mL of DNase I) depict the different ways in which loss of structural stability occurs, leading to different diffusion coefficient values (scale bar = 100 nm).

    Article Snippet: The final concentration of the DNA origami nanostructures was determined via the NanoDrop UV-Vis spectrophotometer (Thermo Fisher Scientific) by measuring the absorption at a wavelength of 260 nm.

    Techniques: Diffusion-based Assay, Solvent, Viscosity, Concentration Assay, Incubation, Control